Nicotinic Stimulation Produces Multiple Forms of Increased Glutamatergic Synaptic Transmission
نویسندگان
چکیده
منابع مشابه
Nicotinic stimulation produces multiple forms of increased glutamatergic synaptic transmission.
Synaptic modulation and long-term synaptic changes are thought to be the cellular correlates for learning and memory (Madison et al., 1991; Aiba et al., 1994, Goda and Stevens, 1996). The hippocampus is a center for learning and memory that receives abundant cholinergic innervation and has a high density of nicotinic acetylcholine receptors (nAChRs) (Wada et al., 1989; Woolf, 1991). We report t...
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Objective(s) Nicotinic acetylcholine receptors (nAChRs) regulate epileptiform activity and produce a sustained pro-epileptogenic action within the hippocampal slices. In the present study, we investigated the effect of nAChRs on evoked glutamatergic synaptic transmission in area CA3 and CA1 of rat hippocampal slices to identify possible excitatory circuits through which activation of nAChRs pr...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1998
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.18-18-07075.1998